![]() ![]() ![]() Bound impurities are removed from the beads by cleaning-in-place (CIP) procedures using NaOH and in most cases, a solvent.The multimodal ligands ensure strong binding with most impurities over a wide range of pH and salt concentrations.The core of each bead is functionalized with ligands that are both hydrophobic and positively charged, resulting in a highly efficient multimodal binding of various contaminants small enough to enter the core.The inactive shell excludes large molecules (cut off ∼ Mr 700 000 ) from entering the core through the pores of the shell. 700, 25 mL 2,723.18 GE 17548102 17548102 Capto Core 700, 100 mL.Capto Core 700 is composed of a ligand-activated core and inactive shell.Convenient small-scale purification, process development, and scale-up using prepacked HiTrap and HiScreen columns.Straightforward optimization due to flowthrough chromatography and robust performance.Significantly improved productivity and higher flow rates compared with gel filtration methods.For intermediate purification and polishing of viruses and other large biomolecules (Mr > 700 000) in flowthrough mode. Aplicaciones Productos Servicios Documentos Asistencia técnica.The novel core bead technology and multimodal, octylamine ligand give Capto Core 700 dual functionality, size exclusion, and binding chromatography in one chromatography medium (resin). ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |